The main objective of this research was to determine the mediating role of social axioms between basic psychological needs and subjective well-being in the Romanian cultural context and to conduct a cross-cultural comparative analysis between the Romanian and UK cultural contexts. During the development of this research, the world experienced a pandemic. As a result, the author formulated an additional objective, analysed through the prism of a natural experiment with the variable COVID-19. Hence, comparing axioms, needs, and well-being before and during the pandemic provides unique insights into the impact of a global crisis on these variables. The results show that in Romanian culture, only social cynicism mediates the relationship between needs and well-being. In the UK cultural context, both social cynicism and reward for application mediate the relationship between needs and well-being. Subjective well-being tends to be associated with high linguistic performance in Romanianand English. For both Romanian and UK participants, social cynicism mediates the relationship between the need for competence and well-being, leading to an indirect effect of improving well-being.