Mud Crabs become one of the commercially important aquaculture species with their increased global acceptance as high quality seafood as well as their substantial socio-economic role in artisanal coastal fisheries in many tropical and subtropical Asian countries. Sudden fluctuations in market prices, inadequate and poor quality of seed crab at higher prices, improper quality of feed ingredient, lack of strong domestic demand for mud crab, and poor transport facility in the remote rural areas were identified as the key factors for occasional loss in fattening business. In addition, most of the fatteners did not get any training on technical aspects of crab fattening or financial support at lower interest rates. The development of crab seed hatchery, artificial feed for crab, and strongest marketing network are addressed as crux issues for the sustainability of mud crab aquaculture in Bangladesh.