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Solubility Enhancement - Wagh, Vinod;Jagtap, Vaibhav
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Currently only 8% of new drug candidates have both high solubility and permeability. More than 40% of potential drug products suffer from poor water solubility. This frequently results in potentially important products not reaching the market or not achieving their full potential. Experience with solid dispersions over the last 20-30 years indicates that this is a very fruitful approach to improving the release rate and oral bioavailability of poorly water soluble drugs. So this article highlights technology various approaches for the preparation of solid dispersion, technology involved, detail description of poorly water soluble drugs & carriers.…mehr

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Produktbeschreibung
Currently only 8% of new drug candidates have both high solubility and permeability. More than 40% of potential drug products suffer from poor water solubility. This frequently results in potentially important products not reaching the market or not achieving their full potential. Experience with solid dispersions over the last 20-30 years indicates that this is a very fruitful approach to improving the release rate and oral bioavailability of poorly water soluble drugs. So this article highlights technology various approaches for the preparation of solid dispersion, technology involved, detail description of poorly water soluble drugs & carriers.
Autorenporträt
Mr. Vinod T. Wagh. M. Pharm: Pharmaceutics, Assistant Professor in NES's Gangamai College of Pharmacy. Complited B. Pharm (2009)from S.M.B.T. College of Pharmacy, Pune University, Pune., M. Pharm (2012) from DCS's A.R.A. College of Pharmacy, North Maharashtra University, Jalgaon.