Solubility: Significance and Techniques for its Enhancement - Bhatia, Meenakshi;Lohan, Sunidhi
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Solubility is one of the most critical preformulation properties that have a significant impact on performance of a molecule. To achieve desired pharmacological response solubility is one of the important parameters that is responsible for achieving desired concentration of drug in systemic circulation. Poor solubility imparting slow dissolution of drugs, has been a major challenge in drug discovery and development.Therefore to enhance the solubility and dissolution of poorly soluble drugs a number of approaches have been developed. This piece of work is the compilation of techniques to enhance the dissolution of drugs.…mehr

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Produktbeschreibung
Solubility is one of the most critical preformulation properties that have a significant impact on performance of a molecule. To achieve desired pharmacological response solubility is one of the important parameters that is responsible for achieving desired concentration of drug in systemic circulation. Poor solubility imparting slow dissolution of drugs, has been a major challenge in drug discovery and development.Therefore to enhance the solubility and dissolution of poorly soluble drugs a number of approaches have been developed. This piece of work is the compilation of techniques to enhance the dissolution of drugs.
Autorenporträt
Os autores pertencem ao Departamento de ciências farmacêuticas, Guru Jambheshwar University of Science & Technology, Hisar, Índia, trabalhando no campo da melhoria da solubilidade de medicamentos pouco solúveis.