Somatic Hypermutation
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Somatic hypermutation (or SHM) is a mechanism inside cells that is part of the way the immune system adapts to the new foreign elements that confront it (for example, microbes). SHM diversifies the receptors used by the immune system to recognize foreign elements (antigens) and allows the immune system to adapt its response to new threats during the lifetime of an organism. Somatic hypermutation involves a programmed process of mutation affecting the variable regions…mehr

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Somatic hypermutation (or SHM) is a mechanism inside cells that is part of the way the immune system adapts to the new foreign elements that confront it (for example, microbes). SHM diversifies the receptors used by the immune system to recognize foreign elements (antigens) and allows the immune system to adapt its response to new threats during the lifetime of an organism. Somatic hypermutation involves a programmed process of mutation affecting the variable regions of immunoglobulin genes. Unlike many other types of mutation, SHM affects only individual immune cells, and the mutations are not transmitted to offspring.