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High Quality Content by WIKIPEDIA articles! In applied mathematics, the two-dimensional Spectral signal-to-noise ratio (SSNR) measures the normalised cross-correlation coefficient between several two-dimensional images over corresponding rings in Fourier space, i.e., as a function of spatial frequency, a multi-particles extension of the Fourier ring correlation (FRC), which is related to the Fourier shell correlation. The SSNR is a popular method for finding the resolution of a class average in cryo-electron microscopy.