Owing to the widespread use of paracetamol in different kinds of pharmaceutical preparations, rapid and sensitive methods for the determination of paracetamol are being investigated. The author therefore explores on a very sensitive, simple but less expensive method of spectrophotometric determination of paracetamol using Zirconium(IV) oxide and ammonium trioxo vanadate(V). There is no doubt that the text will be of tremendous benefit to pharmaceutical companies, researchers,students and indeed to every reader.