Sphingolipid-Mediated Signal Transduction

Herausgegeben:Hannun, Yusuf A.

• Broschiertes Buch

Produktbeschreibung

Lipid-derived molecules are increasingly appreciated as key regulators of cell responses and signal transduction. Sphingolipid-derived bioactive molecules are emerging as critical regulators of some of the most exciting and, until recently, poorly-understood areas of biology such as growth suppression, programmed cell death and tumor invasion. Written by leading investigators in these areas of study, this book presents a thorough, current and accessible review of how sphingolipids function to regulate these important activities.

Produktdetails

• Molecular Biology Intelligence Unit
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-662-22427-4
• Softcover reprint of the original 1st ed. 1997
• Seitenzahl: 212
• Erscheinungstermin: 13. November 2013
• Englisch
• Abmessung: 229mm x 152mm x 12mm
• Gewicht: 315g
• ISBN-13: 9783662224274
• ISBN-10: 3662224275
• Artikelnr.: 39915241

Inhaltsangabe

1. Introduction and Overview.- 2. Ceramide: A Stress Response Mediator Involved in Growth Suppression.- 3. Ceramide and Inflammation.- 4. A Role for Ceramide in Meiosis.- 5. Ceramide, Aging and Cellular Senescence.- 6. Ceramide, a Mediator of Cytosine Arabinoside Induced Apoptosis.- 7. The Use of Cerebroside Synthase Inhibitors as Probes for Assessing the Metabolism and Function of Sphingolipids.- 8. Role of Sphingolipids in Regulating the Phospholipase D Pathway and Cell Division.- 9. Sphingosine-l-Phosphate: Member of a New Class of Lipid Second Messengers.- 10. Functional Roles of Glycosphingolipids and Sphingolipids in Signal Transduction.- 11. Ceramide Synthase and Ceramidases in the Regulation of Sphingoid Base Metabolism.- 12. Ceramidase and Signal Transduction.