Spike & Dru is a trade paperback collecting comic stories based on the Buffy The Vampire Slayer television series. The book contains four stories, all starring the characters Spike and Drusilla. In 1933, Spike and Dru are at the World's Fair. However, some very vengeful and deadly vampire hunters want vengeance against Spike for killing their relative Xin Rong. Spike and Dru are travelling to Sunnydale, but first stop off at St. Louis to try some riverboat gambling. The detour ends up less relaxing than they might have hoped.