Spindle Checkpoint
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In order to preserve one cell's identity and its proper functioning, it is necessary to maintain constant the appropriate number of chromosomes after each cell division. Only one error generating cells with more or less chromosomes than expected (a situation termed aneuploidy), might lead in best cases to cell death, or alternatively it might generate catastrophic phenotypic results. The mechanisms verifying that all the requirements to pass to the next phase in the…mehr

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In order to preserve one cell's identity and its proper functioning, it is necessary to maintain constant the appropriate number of chromosomes after each cell division. Only one error generating cells with more or less chromosomes than expected (a situation termed aneuploidy), might lead in best cases to cell death, or alternatively it might generate catastrophic phenotypic results. The mechanisms verifying that all the requirements to pass to the next phase in the cell cycle have been fulfilled are called checkpoints. All along the cell cycle, there are different checkpoints.