Examining all aspects of stealth liposomes, this book provides a historical perspective, describes liposome behavior in biological systems, and a reviews the role of glycolipid-containing liposome systems. It presents theoretical considerations followed by contributions that provide experimental verification of the various theoretical models and discusses chemistry, biology, and pharmacology. Topics include the use of sterically stabilized liposomes loaded with anticancer agent doxorubican in humans, preclinical studies in various tumors, sterically stabilized liposomes with attached antibodies, and other applications.…mehr
Examining all aspects of stealth liposomes, this book provides a historical perspective, describes liposome behavior in biological systems, and a reviews the role of glycolipid-containing liposome systems. It presents theoretical considerations followed by contributions that provide experimental verification of the various theoretical models and discusses chemistry, biology, and pharmacology. Topics include the use of sterically stabilized liposomes loaded with anticancer agent doxorubican in humans, preclinical studies in various tumors, sterically stabilized liposomes with attached antibodies, and other applications.
Introduction D.D. Lasic and F.J. MartinForeword A.D. BanghamStealth (R) Liposomes: From Steric Stabilization to Targeting D. PapahadjopoulosFate of Liposomes In Vivo and Its Control: An Historical Perspective G. GregoriadisEffect of Surface Modification with Glycolipids and Polysaccharides on In Vivo Fate of Liposomes P.C. Ghosh and B.K. BachhawatStabilization of Colloidal Dispersions by Grafted Polymers O. Borisov P. Auroy and L. AuvrayPhysical Properties of Polymer-Grafted Bilayers K. Hristova and D. NeedhamMolecular Mechanism of Liposome and Immunoliposome Steric Protection with Poly (Ethylene Glycol): Theoretical and Experimental Proofs of the Role of Polymer Chain Flexibility V.P. Torchilin M.I. Papisov A.A. Bogdanov V.S. Trubetskoy and V.G. OmelyanenkoMeasurement of the Range and Magnitude of the Repulsive Pressure between PEG-Coated Liposomes T.J. McIntosh A.K. Kenworthy and D. NeedhamModulation and Modeling of Interaction Forces between Lipid Bilayers Exposing Terminally Grafted Polymer Chains T.L. Kuhl D.E. Leckband D.D. Lasic and J.N. IsraelachviliPolyetheylene Glycol-Lipid Conjugates S. ZalipskyBiological Properties of Sterically Stabilized Liposomes M.C. Woodle M.S. Newman and P.K. WorkingMechanism of Stealth (R) Liposomes Accumulation in Some Pathological Tissues S.K. Huang F.J. Martin D.S. Friend and D. PapahadjopoulosExtravasation of Stealth (R) Liposomes into Tumors: Direct Measurement of Accumulation and Vascular Permeability Using a Skin-Flap Window Chamber M. Dewhirst and D. NeedhamPharmacokinetics and Antitumor Activity of Anthracyclines Precipitated in Sterically Stabilized (Stealth (R)) Liposomes D.D. LasicTissue Uptake and Therapeutic Effects of Stealth (R) Doxorubicin J. Vaage and E. BarberaTherapeutic Application of Vincristine in Conventional and Sterically Stabilized Liposomes P.S. UsterStealth (R) Liposomes as a Drug Sustained Release System for 1-b-D-Arabinosylfuranosylcytosine (Cytosine Arabinoside)
Introduction D.D. Lasic and F.J. MartinForeword A.D. BanghamStealth (R) Liposomes: From Steric Stabilization to Targeting D. PapahadjopoulosFate of Liposomes In Vivo and Its Control: An Historical Perspective G. GregoriadisEffect of Surface Modification with Glycolipids and Polysaccharides on In Vivo Fate of Liposomes P.C. Ghosh and B.K. BachhawatStabilization of Colloidal Dispersions by Grafted Polymers O. Borisov P. Auroy and L. AuvrayPhysical Properties of Polymer-Grafted Bilayers K. Hristova and D. NeedhamMolecular Mechanism of Liposome and Immunoliposome Steric Protection with Poly (Ethylene Glycol): Theoretical and Experimental Proofs of the Role of Polymer Chain Flexibility V.P. Torchilin M.I. Papisov A.A. Bogdanov V.S. Trubetskoy and V.G. OmelyanenkoMeasurement of the Range and Magnitude of the Repulsive Pressure between PEG-Coated Liposomes T.J. McIntosh A.K. Kenworthy and D. NeedhamModulation and Modeling of Interaction Forces between Lipid Bilayers Exposing Terminally Grafted Polymer Chains T.L. Kuhl D.E. Leckband D.D. Lasic and J.N. IsraelachviliPolyetheylene Glycol-Lipid Conjugates S. ZalipskyBiological Properties of Sterically Stabilized Liposomes M.C. Woodle M.S. Newman and P.K. WorkingMechanism of Stealth (R) Liposomes Accumulation in Some Pathological Tissues S.K. Huang F.J. Martin D.S. Friend and D. PapahadjopoulosExtravasation of Stealth (R) Liposomes into Tumors: Direct Measurement of Accumulation and Vascular Permeability Using a Skin-Flap Window Chamber M. Dewhirst and D. NeedhamPharmacokinetics and Antitumor Activity of Anthracyclines Precipitated in Sterically Stabilized (Stealth (R)) Liposomes D.D. LasicTissue Uptake and Therapeutic Effects of Stealth (R) Doxorubicin J. Vaage and E. BarberaTherapeutic Application of Vincristine in Conventional and Sterically Stabilized Liposomes P.S. UsterStealth (R) Liposomes as a Drug Sustained Release System for 1-b-D-Arabinosylfuranosylcytosine (Cytosine Arabinoside)
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