**Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024** Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell…mehr
**Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024** Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more. The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.
Preface Akon Higuchi Yinghong Zhou and Shih-Hwa Chiou 1. Introduction to stem cells Zeyu Tian Tao Yu Jun Liu Ting Wang and Akon Higuchi 2. Engineered adult stem cells: current clinical trials status of disease treatment Pingping Han Corey Stephan Moran Chun Liu Rebecca Griffiths Yinghong Zhou and Sao Ivanovski 3. Xeno-free culture and proliferation of hPSCs on 2D biomaterials Ting Wang Tao Yu Chang-Yen Tsai Zhao-Yu Hong Wen-Hui Chao Yi-Shuo Su Suresh Kumar Subbiah Remya Rajan Renuka Shih-Tien Hsu Gwo-Jang Wu and Akon Higuchi 4. Stem cell culture and differentiation in 3-D scaffolds Yasuhiko Tabata Idaszek Joanna and Akon Higuchi 5. Current trends and promising clinical utility of IPSC-derived MSC (iMSC) Shih-Hwa Chiou Alan Han Kiat Ong Shih-Jie Chou Ahmed Faris Aldoghachi Jit Kai Loh Nalini Devi Verusingam Yi-Ping Yang and Yueh Chien 6. Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells Saeko Akiyama Noriaki Saku Shoko Miyata Kenta Ite Hidenori Nonaka Masashi Toyoda Akihide Kamiya Tohru Kiyono Tohru Kimura Mureo Kasahara and Akihiro Umezawa 7. Cardiac cell sheet engineering for regenerative medicine and tissue modeling Katsuhisa Matsuura and Tatsuya Shimizu 8. Mesenchymal stem cells in osteoarthritis: The need for translation into clinical therapy Feng Gao Xinzhan Mao and Xiaoxin Wu 9. hPSC-derived RPE transplantation for the treatment of macular degeneration Qian Liu Jun Liu and Akon Higuchi 10. Universal and hypoimmunogenic pluripotent stem cells for clinical usage Tzu-Cheng Sung Kailibinuer Maitiruze Jiandong Pan Jian Gong Yongheng Bai Xiaodong Pan and Akon Higuchi 11. Clinical Usage of Dental Stem Cells and Their Derived Extracellular Vesicles Yinghong Zhou Tian Xu Cong Wang Pingping Han and Sao Ivanovski 12. Vascularization of cutaneous wounds by stem cells Motaharesadat Hosseini and Abbas Shafiee 13. Application of IPSC and Müller glia derivatives in retinal degenerative diseases Guoge Han Pinghui Wei and Quanhong Han 14. Pluripotent Stem Cells as a Therapy for Type 1 Diabetes Bernard E. Tuch Iris S. Cheng Hoang Phuc Dang Hui Chen and Tim R. Dargaville 15. Stem cell challenges and opportunities Kenta Ite Masashi Toyoda Saeko Akiyama Shin Enosawa Saeko Yoshioka Takaaki Yukitake Mayu Yamazaki-Inoue Kuniko Tatsumi Hidenori Akutsu Hiroshi Nishina Toru Kimura Naoko Otani Atsuko Nakazawa Akinari Fukuda Mureo Kasahara and Akihiro Umezawa
Preface Akon Higuchi Yinghong Zhou and Shih-Hwa Chiou 1. Introduction to stem cells Zeyu Tian Tao Yu Jun Liu Ting Wang and Akon Higuchi 2. Engineered adult stem cells: current clinical trials status of disease treatment Pingping Han Corey Stephan Moran Chun Liu Rebecca Griffiths Yinghong Zhou and Sao Ivanovski 3. Xeno-free culture and proliferation of hPSCs on 2D biomaterials Ting Wang Tao Yu Chang-Yen Tsai Zhao-Yu Hong Wen-Hui Chao Yi-Shuo Su Suresh Kumar Subbiah Remya Rajan Renuka Shih-Tien Hsu Gwo-Jang Wu and Akon Higuchi 4. Stem cell culture and differentiation in 3-D scaffolds Yasuhiko Tabata Idaszek Joanna and Akon Higuchi 5. Current trends and promising clinical utility of IPSC-derived MSC (iMSC) Shih-Hwa Chiou Alan Han Kiat Ong Shih-Jie Chou Ahmed Faris Aldoghachi Jit Kai Loh Nalini Devi Verusingam Yi-Ping Yang and Yueh Chien 6. Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells Saeko Akiyama Noriaki Saku Shoko Miyata Kenta Ite Hidenori Nonaka Masashi Toyoda Akihide Kamiya Tohru Kiyono Tohru Kimura Mureo Kasahara and Akihiro Umezawa 7. Cardiac cell sheet engineering for regenerative medicine and tissue modeling Katsuhisa Matsuura and Tatsuya Shimizu 8. Mesenchymal stem cells in osteoarthritis: The need for translation into clinical therapy Feng Gao Xinzhan Mao and Xiaoxin Wu 9. hPSC-derived RPE transplantation for the treatment of macular degeneration Qian Liu Jun Liu and Akon Higuchi 10. Universal and hypoimmunogenic pluripotent stem cells for clinical usage Tzu-Cheng Sung Kailibinuer Maitiruze Jiandong Pan Jian Gong Yongheng Bai Xiaodong Pan and Akon Higuchi 11. Clinical Usage of Dental Stem Cells and Their Derived Extracellular Vesicles Yinghong Zhou Tian Xu Cong Wang Pingping Han and Sao Ivanovski 12. Vascularization of cutaneous wounds by stem cells Motaharesadat Hosseini and Abbas Shafiee 13. Application of IPSC and Müller glia derivatives in retinal degenerative diseases Guoge Han Pinghui Wei and Quanhong Han 14. Pluripotent Stem Cells as a Therapy for Type 1 Diabetes Bernard E. Tuch Iris S. Cheng Hoang Phuc Dang Hui Chen and Tim R. Dargaville 15. Stem cell challenges and opportunities Kenta Ite Masashi Toyoda Saeko Akiyama Shin Enosawa Saeko Yoshioka Takaaki Yukitake Mayu Yamazaki-Inoue Kuniko Tatsumi Hidenori Akutsu Hiroshi Nishina Toru Kimura Naoko Otani Atsuko Nakazawa Akinari Fukuda Mureo Kasahara and Akihiro Umezawa
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