Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science-medicine, the latest technology, and clinical economics-the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the…mehr
Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science-medicine, the latest technology, and clinical economics-the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more.
Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Marek Los studied medicine at Jagiellonian Univ., Krakow, Poland. He obtained his doctoral degree from Univ. Heidelberg, in 1995, and habilitation (academic teaching license) in Molecular Medicine, from Univ. Muenster in 2002. He is currently the head of Department of Molecular Biology, Faculty of Pharmacy, Silesian University of Medicine, in Katowice, Poland. He is also assoc. editor at The European Journal of Pharmacology, holds 2 Visiting Professorships at other Polish universities, and a 'Senior Scientific Adviser' position at Linkocare AB, Linköping, Sweden. Linkocare's core business is the production of artificial corneas. Dr. Los (co-)authors about 150 scientific papers, some of them highly-cited, edited several books and volumes. He has been serving as member of a number of editorial boards of scientific journals, as well as on various grant review committees in the Europe and in Canada. Dr. Los pursues various research projects within area of oncology, targeted cancer the
rapies and Regenerative Medicine. His most important scientific achievements were the description of involvement of caspase family of proteases in CD95 (APO-1/Fas) mediated apoptosis, (Los et al., 1995; Nature 375: 81-83), and the discovery of the role of kinase Akt both in the regulation of cell survival and cell death of cancer cells (Maddika et al., 2008, J. Cell Sci.; Maddika et al., 2009, Mol. Cell. Biol.). His research interest encompasses cancer immunology, cell death execution pathways, as well as cancer stem cell biology, epigenetic reprogramming (production of iPS-cells), as well as transdifferentiation technologies.
Inhaltsangabe
1. Introduction and historic perspective 2. Stem cells - definition and types of stem cells, stemness and differentiation 3. Modern methods of obtaining stem cells - overview of reprogramming methods 4. Transdifferentiation - direct way to obtain cell precursors for regenerative medicine 5. Generation of organs based on repopulation of cell-free extracellular matrix scaffolds 6. Introduction to transplantology 7. Biomaterials 8. Overview of technologies applied for biomaterial production 9. Quality control of biomaterials 10. Methods of biomaterial-aided cell delivery 11. Example of successful biomaterial-based artificial organ - artificial cornea 12. Example of successful biomaterial-based artificial organ - artificial hip 13. Example of successful biomaterial-based artificial organ - artificial skin 14. Biomatreials, and artificial tissues - risk assessment 15. Regenerative medicine in numbers 16. Regenerative medicine - further development
1. Introduction and historic perspective 2. Stem cells - definition and types of stem cells, stemness and differentiation 3. Modern methods of obtaining stem cells - overview of reprogramming methods 4. Transdifferentiation - direct way to obtain cell precursors for regenerative medicine 5. Generation of organs based on repopulation of cell-free extracellular matrix scaffolds 6. Introduction to transplantology 7. Biomaterials 8. Overview of technologies applied for biomaterial production 9. Quality control of biomaterials 10. Methods of biomaterial-aided cell delivery 11. Example of successful biomaterial-based artificial organ - artificial cornea 12. Example of successful biomaterial-based artificial organ - artificial hip 13. Example of successful biomaterial-based artificial organ - artificial skin 14. Biomatreials, and artificial tissues - risk assessment 15. Regenerative medicine in numbers 16. Regenerative medicine - further development
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