Beginning with Stem cell definition and classification, a good narrative synthesis of all stem cells has been included. Almost all aspects of Stem Cells from Exfoliated Deciduous teeth has been covered. Extensive literature survey has been carried out on uses of SHED Cells. Isolation protocols, SHED cell banking have been elaborately explained. Recent studies using SHED Cells for dental tissue regeneration has been explained. Role of SHED Cells in Regenerative Endodontic procedures have been focused.