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Companies frequently operate in an uncertain environment and many real life production planning problems imply volatility and stochastics of the customer demands. Thereby, the determination of the lot-sizes and the production periods significantly affects the profitability of a manufacturing company and the service offered to the customers. This thesis provides practice-oriented formulations and variants of dynamic lot-sizing problems in presence of restricted production resources and demand uncertainty. The demand fulfillment is regulated by service level constraints. Additionally, integrated production and remanufacturing planning under demand and return uncertainty in closed-loop supply chains is addressed. This book offers introductions to these problems and presents approximation models that can be applied under uncertainty. Comprehensive numerical studies provide managerial implications. The book is written for practitioners interested in supply chain management and production as well as for lecturers and students in business studies with a focus on supply chain management and operations management.