Rationalisation aims to direct partners in order to minimise wastage of resources due to the co-presence of several of them on the same sites and in the same Health Zones (ZS). This process will take place in three stages: localisation in a site by the end of 2015, zonalisation by 2016 and finally provincialisation by the end of 2018. Important steps have been taken to manage the transition smoothly, including the preparation of transition plans in the Provincial Health Divisions (DPS), with the involvement of the ZSs concerned, and the establishment of a buffer stock to manage any stock shortages. Finally, an agreement between the PNLS and the main partners was signed to sanction the redistribution of the ZS to the support partners. A number of lessons were learned from this process, including the leadership of the NACP, which was the driving force behind it, the support of the partners who adhered to the NACP's vision, the establishment of a framework for partner consultation on the NACP and, finally, the anticipation of implementation problems. This book is therefore aimed at managers of HIV/AIDS programmes.