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The Caribbean Region is second only to Africa in the impact of HIV/AIDS. The Caribbean Community (CARICOM) has responded to this challenge by promoting a multisectoral response to the epidemic. UNESCO has provided regional leadership in strengthening the education sector component of this response. In 2005, UNESCO launched, with CARICOM and the World Bank, a regional dialogue involving representatives of Ministries of Education, national HIV/AIDS coordinating councils, development partners, and regional institutions providing leadership in the HIV response, which led tot he development and endorsement of a regional Proposal for Action: Accelerating the Education Sector Response to HIV&AIDS in the Caribbean Region.