Psychological stress if sustained over an extended period can have deleterious effects on the body representing an important example of mind-body interaction.Sufficient evidence exists to prove that stress reduces the body's normal immune response.Psychosocial measures of stress associated with financial strain and distress (manifested as depression) are significant risk indicators for periodontal disease in adults.Coping mechanisms/ behaviour play a major role.This book highlights on the same as how psychological stress affects the periodontium and what are the ways to minimise the effect.