Tuberculosis (hereafter, TB) lesions have been found in the Egyptian mummies perhaps as early as 3700 BC.TB has become the most important infections disease in the world,it kills more than 1 million women per year.Individuals afflicted with TB have many illness-related stressors such as pain, financial problem and dependency, stigma and threat to self-esteem. The way individuals cope with illness-related stressors can influence their emotional, physiological and behavioral reactions. Therefore, there is need to investigate how individuals afflicted with TB cope with illness- relate stressors in order to facilitate patient s optimal adaptation to TB. Nurses can assist patient by providing support, information, critical analysis and alternative problem- solving strategies to further improve the quality of life of these patients.