Structural Bioinformatics
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The genomics and post-genomics revolutions in biology have led to a widespread appreciation of the importance of three-dimensional structural data for understanding function. This text aims to provide a basic understanding of the theories, associated algorithms, resources and tools used in structural bioinformatics. The reader should emerge with the ability to make effective use of protein, DNA, RNA, carbohydrate and complex structures to better understand biological function. Moreover, the book draws a clear connection between structural studies and the rational design of new therapies.