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The purpose of this study was to investigate the relationship between nurses' structural empowerment status and their job stress and job burnout (case study: Nurses in government hospitals in Tehran). Structural empowerment is an internal motivating factor that reflect the active role of employees in the organization. Working environment with support are the most important factor in creating job satisfaction in nurses. Nursing managers, with the knowledge of the results of this research, can provide an appropriate work environment for nurses with increasing organizational support. Considering that burnout deduces the quality of nursing care and decrease patient satisfaction, stress prevention has been effective in improving nursing care and increasing patient satisfaction and reducing the occupational stress of nurses and preventing burnout in the workplace.