Adversity Quotient (AQ) is an innate ability that enables people turn their adverse situations into life-changing advantage. Determining students'AQ and its influence in relation to other factors that affect achievement is likely to provide greater understanding and better prediction of academic achievement. Many researches have been carried out on this concept without focussing on its combined impacts with student-teacher psychological factors on academic achievement among secondary school students. The study, therefore, examined the prediction effects of AQ and student-teacher psychological constructs (Students' attribution; students' school connectedness; teachers' self-efficacy; school type; gender; school location and age) on students' academic achievement in Mathematics and English Language in the West African Senior School Certificate Examination (WASSCE) in Southwestern Nigeria.