Single crystals are one of the most important groups of materials due to their continuous, uniform, and highly-ordered structure which enables them to possess unique properties.semiconductors and photovoltaics is the greatest use of single-crystal technology today. In photovoltaics, the most efficient crystal structure will yield the highest light-to-electricity conversionBacterial infection is one of the most serious threats to public health. Despite traditional antibiotics therapy provides an effective approach to combat pathogenic bacteria, the long-term use and overuse of antibiotics result in the evolution of bacteria with antibiotic resistance. Recent progress in nanotechnology offers novel opportunities to overcome the obstacle with independence of antibiotics. Metal-organic frameworks (MOFs) have emerged as new tools to combat bacterial infection in biomedical and food packaging fields.