Studies on Membrane-Associated Proteins in Exocytosis and Endocytosis - Tong, Jiansong
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"Biophysical Studies with Membrane-Associated Protein in Synaptic Exocytosis and Endocytosis" explored detailed mechanisms for understanding how membrane proteins play their roles ¿locally¿ in exact biological pathways. Synaptobrevin2, a protein required for synaptic exocytosis, forms a parallel dimer from an open-scissor like structure by cholesterol lipid on the membrane to facilitate the membrane fusion process. Epsin1, which is involved in endocytosis, binds with lipid PIP2 to adjust its random coil to a helix to help tabulate the membrane. Therefore, this book provides excellent models to…mehr

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Produktbeschreibung
"Biophysical Studies with Membrane-Associated Protein in Synaptic Exocytosis and Endocytosis" explored detailed mechanisms for understanding how membrane proteins play their roles ¿locally¿ in exact biological pathways. Synaptobrevin2, a protein required for synaptic exocytosis, forms a parallel dimer from an open-scissor like structure by cholesterol lipid on the membrane to facilitate the membrane fusion process. Epsin1, which is involved in endocytosis, binds with lipid PIP2 to adjust its random coil to a helix to help tabulate the membrane. Therefore, this book provides excellent models to explain why different membrane proteins required in different biological processes. It will also help us to better understand the features of membrane proteins in the research field.
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Autorenporträt
Dr. Tong currently is a Research Associate in Department of Cellular and Molecular Biology at The Scripps Research Institute at La Jolla, CA. He obtained his PhD in Biochemistry from Department of Biochemistry, Biophysics, and Molecular Biology at Iowa State University at Ames, Iowa. He is an expert working on membrane protein structure.