Studies on T Cell Signaling Mechanisms - Yadav, Deepa
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T cells are crucial to immune response. They are activated when TCR recognizes foreign invader on MHC molecules. Activation of T cells is associated with type II phosphatidylinositol (PtdIns) 4-kinases beta. Type II PtdIns 4-kinases play a role in microbial pathogenicity and neuronal signaling. So, understanding of type II PtdIns 4-kinases function, their regulators and signaling events may help in development of rational drug design for immunomodulators and possibly in cancer metastasis.

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Produktbeschreibung
T cells are crucial to immune response. They are activated when TCR recognizes foreign invader on MHC molecules. Activation of T cells is associated with type II phosphatidylinositol (PtdIns) 4-kinases beta. Type II PtdIns 4-kinases play a role in microbial pathogenicity and neuronal signaling. So, understanding of type II PtdIns 4-kinases function, their regulators and signaling events may help in development of rational drug design for immunomodulators and possibly in cancer metastasis.
Autorenporträt
Deepa Yadav, MTech CSE, Università NorthCap. La dott.ssa Akansha Singh lavora attualmente come professore associato presso la School of Computing Science dell'Università Galgotias. Il dott. Krishna Kant Singh lavora attualmente come professore associato presso il Dipartimento di Elettronica e Comunicazione del GL Bajaj Institute of Technology and Management.