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The book contains the research work carried out by the author. the work includes the synthesis of Benzofuran-1,3,4-Oxadiazole combined molecole. This combined molecule is reacted with p-amini salicylic acid ligand in order to form chelate complex. Elemental analysis, different type of spectroscopy technique and analytical techniques are used to find out the characteristic properties of the chelate. Antimicrobial activities of this chelates are studied and compared to find out the effect of chelate on micro-organism. The research work is carried out under the supervision of Dr G.D.Acharya, HOD, department of chemistry, R.R.Mehta college of science and C.L.Parikh college of commerce, palanpur, india. The research work is affiliated to Hemchandracharya North Gujarat University, Patan, India.