Subcellular Biochemistry

Volume 7
Herausgegeben:Roodyn, Donald B.

• Broschiertes Buch

Produktbeschreibung

The broad aim of SUBCELLULAR BIOCHEMISTRY is to present an inte grated view of the cell in which artificial barriers between disciplines are bro ken down. The contents of Volume 7 illustrate the interconnections between initially unrelated fields of study and show strikingly how advances along one front become possible because of parallel successes in another. Current research into cell organelles and membrane systems is not only concerned with the elucidation of their structure and function. It also asks such questions as: Which regions of the cell are concerned in the bioassembly of the organelle? How are organelle and membrane precursors transported from the site of syn thesis to the newly formed cell constituent? What genetic systems control the biosynthesis and assembly of cell components and how do these systems inter act? How did the various cell constituents evolve? How did the genetic and biosynthetic systems making the organelles themselves evolve? The search for the answer to such questions has placed organelle biochemistry on a different level than that of the more restricted studies of the 1950s and early 1960s and promises to produce some fascinating and surprising results. Volume 7 opens with a detailed chapter by A. A. Hadjiolov on the bio genesis of ribosomes of eukaryotes. The general arrangement of ribosomal genes is discussed, and there is a full account of their transcription.

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Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4615-7950-2
• Softcover reprint of the original 1st ed. 1980
• Seitenzahl: 436
• Erscheinungstermin: 9. Mai 2012
• Englisch
• Abmessung: 229mm x 152mm x 24mm
• Gewicht: 635g
• ISBN-13: 9781461579502
• ISBN-10: 1461579503
• Artikelnr.: 40767128

Inhaltsangabe

1 Biogenesis of Ribosomes in Eukaryotes.- 1. Introduction.- 2. Ribosomal Genes.- 3. Transcription of Ribosomal RNA Genes.- 4. Processing of Primary Pre-rRNA and Preribosomes.- 5. Regulation.- 6. Concluding Remarks.- 7. References.- 2 The Role of Ribonucleic Acids in the Organization and Functioning of Ribosomes of E. coli.- 1. Introduction.- 2. The Secondary Structures of Ribosomal RNA in Ribosomes.- 3. Compact Folding of RNA in Ribosomal Subunits.- 4. Domain Organization of Ribosomal Subunits.- 5. Role of Ribosomal Proteins in the Organization of RNA Tertiary Structure within Ribosomal Subunits.- 6. Direct Participation of Ribosomal RNA in Ribosome Functioning.- 7. Topography of rRNA in Ribosomes.- 8. Addendum: A Preliminary Model for the Secondary Structure of 16 S Ribosomal RNA.- 9. References.- 3 Aspects of the Role of the Endoplasmic Reticulum in Protein Synthesis.- 1. Introduction.- 2. Membranes of the Endoplasmic Reticulum.- 3. Protein Synthesis.- 4. Polyribosome-Membrane Interactions.- 5. Heterogeneity in the Function of Rough Endoplasmic Reticulum with Respect to Protein Synthesis.- 6. Conclusions.- 7. References.- 4 Biogenesis of Peroxisomes and Glyoxysomes.- 1. Introduction.- 2. Morphology and Topographical Relationship to Other Cellular Organdies.- 3. Biochemical Properties and Metabolic Roles.- 4. Microbody Proliferation.- 5. Models for the Synthesis of Microbody Components and Their Transfer to the Organelles.- 6. The Synthesis of Microbody Components.- 7. References.- 5 The Subcellular Biochemistry of Thyroid.- 1. Introduction.- 2. Cell Fractionation.- 3. Localization of Enzymes and Constituents in Bovine Thyroid Tissue.- 4. Isolation and Characterization of Thyroid Organelles, Subcellular Components, and Membranes.- 5. Summary.- 6. References.- 6 The Molecular Organization of NADH Dehydrogenase.- 1. Introduction.- 2. The Protein Components of NADH Dehydrogenase.- 3. The Protein Structure of NADH Dehydrogenase.- 4. The Phospholipid Components of NADH Dehydrogenase.- 5. Organization of NADH Dehydrogenase in the Membrane.- 6. Conclusion.- 7. References.- 7 Structure-Function Relationships of Micrococcus lysodeikticus Membranes: A Bacterial Membrane Model System.- 1. Introduction.- 2. Ultrastructure of Bacterial Membranes.- 3. Biochemical Characterization of Micrococcus lysodeikticus Membranes.- 4. Antigenic Architecture of the Membrane of M. Lysodeikticus.- 5. Summary and Conclusions.- 6. References.- Some Recent Books in Cell Biochemistry and Biology.- 1. Cell and Membrane Biology.- 2. Genetics and Viruses.- 4. General Biochemistry.