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According to pathologists, they account for 4.8% (Tennsterdt A. et al., 1984). The proportion of skeletal anomalies in hereditary malformations is much higher, in which they reach 90% or more (Laziuk G.I. et al., 1983). Congenital skeletal anomalies are very polymorphic in their clinical manifestations and nosological affiliation. It includes 5 main groups of skeletal anomalies, which in turn are subdivided into subgroups: 1) osteochondrodysplasias-dysplasias due to abnormal growth and development of cartilage and/or bone (growth defects of tubular bones and/or spine, disorganization of…mehr

Produktbeschreibung
According to pathologists, they account for 4.8% (Tennsterdt A. et al., 1984). The proportion of skeletal anomalies in hereditary malformations is much higher, in which they reach 90% or more (Laziuk G.I. et al., 1983). Congenital skeletal anomalies are very polymorphic in their clinical manifestations and nosological affiliation. It includes 5 main groups of skeletal anomalies, which in turn are subdivided into subgroups: 1) osteochondrodysplasias-dysplasias due to abnormal growth and development of cartilage and/or bone (growth defects of tubular bones and/or spine, disorganization of cartilage development and skeletal fibrous components, anomalies of cortical layer density of diaphyses and/or metaphyses formation); 2) bone dysostoses isolated or combined (with involvement of the skull and face, with predominant involvement of the spine or limbs); 3) idiopathic osteolysis - melting of bones with secondary deformities (forms by localization and prevalence); 4) chromosomal aberrations with unusual skeletal anomalies.
Autorenporträt
Kosimhozhiyev Mukhammadjon Ibrohimjon è nato nel 1975. È nato nella città di Andijan della Repubblica dell'Uzbekistan. Dal 1992 al 1998 ha studiato all'Istituto Medico Statale di Andijan. Nel 2002 ha difeso la sua tesi di laurea. Nel 2002 è diventato un candidato di Scienze Mediche. Nel 2011 ha difeso la sua tesi di dottorato.