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Complex macromolecular machinery is responsible for gene-specific and cell-type selective patterns of gene expression. How it works is being revealed by increasingly sophisticated molecular dissection of prokaryotic and eukaryotic cells. In this volume, sixty-seven of the world's leaders in the study of gene transcription review the results and conclusions of their most recent studies. They cover events ranging from activation, through promoter recognition, repression, chromosome structure, chromatin remodeling, initiation and elongation, and the regulation of stopping and starting. Written…mehr

Produktbeschreibung
Complex macromolecular machinery is responsible for gene-specific and cell-type selective patterns of gene expression. How it works is being revealed by increasingly sophisticated molecular dissection of prokaryotic and eukaryotic cells. In this volume, sixty-seven of the world's leaders in the study of gene transcription review the results and conclusions of their most recent studies. They cover events ranging from activation, through promoter recognition, repression, chromosome structure, chromatin remodeling, initiation and elongation, and the regulation of stopping and starting. Written with a broad audience of molecular biologists in mind, extensively illustrated and completed by a masterly overview from Richard Losick, this book is an up-to-date and accessible survey of a topic at the heart of molecular biology and biotechnology.