Actinidic archaea has been related to neurogenetic and neurodevelopmental disorders (Huntington's disease, trisomy 21 and cerebral palsy), chronic congenital and acquired speech disorders (dyslexia, delayed onset speech milestone, delayed recovery from aphasia). The growth of endosymbiotic actinidic archaea leads to neanderthalisation of the human mind-body system and neanderthal metabolonomics has been described in neurogenetic and neurodevelopmental disorders- the Warburg phenotype and hyperdigoxinemia. Digoxin produced by archaeal cholesterol catabolism produces neanderthalisation. Prefrontal cortical atrophy and cerebellar hyperplasia has been related to neurogenetic and neurodevelopmental disorders. This leads on to dysautonomia with sympathetic hyperactivity and parasympathetic neuropathy. A method to modulate archaeal symbiosis and interconverting homo sapien to homo neanderthalis and vice versa is described. This is done by a high fibre versus a low fibre diet, administration of antioxidant antibiotic and colonic microflora from human and cow dung. This can be called as a therapeutic archaeal symbiotic modulated the treatment of neurogenetic and neurodevelopmental disorders
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