Synthesis and Anti-tumor Studies of Steroidal Pyrazolines - Khanam, Hena;Uzzaman, Shams
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The main objective of the present work is description of design, synthesis and characterisation of cholesteryl pyrazolines along with their antitumor studies against human tumor cell lines. The identity of the newly synthesized compounds has been ascertained by IR, 1H NMR, 13C NMR, mass spectrometry and elemental analysis. The First chapter contains introduction regarding importance of cancer, applications of steroids as antitumor agents and biological utility of pyrazoline derivatives. The second and third chapters deal with the synthesis, characterization and stereochemical aspects of…mehr

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Produktbeschreibung
The main objective of the present work is description of design, synthesis and characterisation of cholesteryl pyrazolines along with their antitumor studies against human tumor cell lines. The identity of the newly synthesized compounds has been ascertained by IR, 1H NMR, 13C NMR, mass spectrometry and elemental analysis. The First chapter contains introduction regarding importance of cancer, applications of steroids as antitumor agents and biological utility of pyrazoline derivatives. The second and third chapters deal with the synthesis, characterization and stereochemical aspects of steroidal pyrazolines while fourth chapter embodies antitumor evaluation of the newly synthesized compounds.
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Autorenporträt
Hena Khanam has completed her PhD. from Aligarh Muslim University Aligarh,India on 12,4,2014 in the field of synthetic organic chemistry. She was awarded SRF and BSR fellowship from gov. of India. She has 16 publications in reputed international journals. ¿ Shams Uzzaman is prof. of chemistry AMU Aligarh.He got Commonwealth VisFellowship(UK,1985).