Ala Vasubabu, Haribabu Bollikolla

Synthesis and Bioactive studies of some new C-methylated flavonoids

• Broschiertes Buch

Produktbeschreibung

These compounds possess an array of biological activities and are employed in the treatment of commonly occurring diseases. Literature survey revealed that chalcones, flavanones and aurones possess a broad spectrum of biological activities like antimicrobial, anti-inflammatory, antimalarial, antidepressant, antihistamine, antitubercular and anticancer. This thesis is an endeavor in this direction of synthesis and characterization of such compounds based on 1H NMR, 13CNMR, Mass spectroscopy and elemental analysis. One of the recently isolated flavanone (pisonivanone) from the Pisonia aculeate L was first time synthesized. In the present work a total 30 compounds including a series of 16 chalcones (3a-p) except 3e, 9 flavanones (4a-h&5) and 5 aurones (5a-e) were synthesized for the first time. Two new methods were developed for demethylation of the said flavonoids. Compound-3e and acetophenone-1 were synthesized by efficient alternative methods than earlier available approaches.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 220
• Erscheinungstermin: 10. Juni 2022
• Englisch
• Abmessung: 220mm x 150mm x 14mm
• Gewicht: 346g
• ISBN-13: 9786204977614
• ISBN-10: 620497761X
• Artikelnr.: 64274521

Autorenporträt

Je Dr.A.Vasubabu travaillant comme professeur associé à QIS college of engineering & technology, vengamukkalapalem,Ongole,Andrapradesh depuis 2014. Le travail ci-dessus a été effectué à l'université Acharya Nagarujauna, sous la supervision du Dr.B.Haribabu. Professeur associé en chimie, Département de chimie, Guntur.