The present work describes the synthesis of pyridine derivatives with the adoption of many synthesis methodologies, and also demonstrates their potential in different bioassays. A number of spectroscopic methods were used to identify the synthetic compounds, such as EI-MS, 1H-NMR, 13C-NMR, and HREI-MS. Melting points were also noted for synthetic derivatives. This research study is centered on the literature and inquiries related to the library of synthetic compounds.