Some drugs show allergic action to particular persons. Inflammation plays an important role in variety of diseases like rheumatoid arthritis, septic shock and AIDS. Researchers always search more potent and safer medicine than existing ones. It is essential to study the effect of drugs to multifunctional activity like anti-inflammatory, antioxidant, antidiabitic and antimicrobial. The present work is to discover triazine heterocyclic compounds which can act as novel multifunctional drugs. The present book deals with the synthesis of triazine amine derivatives, triazine piperazine substituted urea and amide, triazine chalcones, triazine pyrazolines, and triazine thiazolidinone derivatives. The biological studies with SAR of the five series of triazine heterocyclic were used for ascertaining their pharmacological and biological importance.