Synthesis and characterization of a pyrazole derivative-¿-CD complex - Louiz, Sonia;Labiadh, Houcine;Abderrahim, Raoudha
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Amino pyrazole belongs to anti-inflammatory class, and is characterized by a low solubility in water. (In order to increase its solubility in water, inclusion complex of amino pyrazole with beta-CD was obtained.)The inclusion complex obtained between AMP and beta-cyclodextrin, was characterized by FT-IR, 1H NMR, 1H-1H NOESY, 13C NMR, DEPT, XHCOR, spectra, through TG analysis, DTA, DSC and Scanning Electron Microscopy (SEM). The stoichiometry of inclusion complex is 1:1 (guest-host) and K stability is 1.1 ×104 M-1.

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Produktbeschreibung
Amino pyrazole belongs to anti-inflammatory class, and is characterized by a low solubility in water. (In order to increase its solubility in water, inclusion complex of amino pyrazole with beta-CD was obtained.)The inclusion complex obtained between AMP and beta-cyclodextrin, was characterized by FT-IR, 1H NMR, 1H-1H NOESY, 13C NMR, DEPT, XHCOR, spectra, through TG analysis, DTA, DSC and Scanning Electron Microscopy (SEM). The stoichiometry of inclusion complex is 1:1 (guest-host) and K stability is 1.1 ×104 M-1.
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Autorenporträt
Soy un Doctor calificado de la Universidad de Carthage. Obtuve cuatro diplomas: en 2008 Diploma de técnico superior en Tecnología Química Industrial, en 2010 Tuve maestría en química y aplicación, en 2012 Diploma de maestría en Sustancias Naturales Terapéuticamente Activas y en 2016 Tesis de grado en química.