A new series of 3N-substituted triazolo-[1,5-c]pyrimidine 7, 8 and 9have been synthesized in good yields (78%-91%) trough a facile method using substituted 2-amino-3-cyano-pyrans 1,2-amino-3-cyano-4-methylfuran 2, 1-Phenyl-3-thiomethyl-5-aminopyrazole-4-carbonitrile 3 as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass, spectral data and DFT at B3LYP.
A new series of 3N-substituted triazolo-[1,5-c]pyrimidine 7, 8 and 9have been synthesized in good yields (78%-91%) trough a facile method using substituted 2-amino-3-cyano-pyrans 1,2-amino-3-cyano-4-methylfuran 2, 1-Phenyl-3-thiomethyl-5-aminopyrazole-4-carbonitrile 3 as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass, spectral data and DFT at B3LYP.
Je suis Chimiste, Enseignant à l'Institut Supérieur des Métiers du Patrimoine, Université de Tunisie et membre du Laboratoire de Synthèse Organique et Hétérocyclique Sélective ¿ Évaluation de l'Activité Biologique, Université El Manar / Doctorat en Chimie, Master en Chimie Supramoléculaire et Master en Sciences Physiques, Université de Carthage.
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