This content covers about Synthesise, Characterizations And Antimicrobials Screenings Of Novel Arylazopyrazoles Part-I. Various antimicrobials and heterocyclic compounds like pyrazole and pyrimidine literature review included in part-I. How pyrazole and pyrimidine derivatives shows numbers of antimicrobials and other pharmaceutical activity whose also found from literature survey. Pyrazole and pyrimidine containing heterocyclic compounds synthesised, which shown in reaction scheme.