![Synthesis and characterization of Triazolo[4,3-c]pyrimidine library - Vilapara, Kalpesh;Gami, Sagar](https://bilder.buecher.de/produkte/57/57553/57553514z.jpg "Synthesis and characterization of Triazolo[4,3-c]pyrimidine library - Vilapara, Kalpesh;Gami, Sagar")
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A novel [1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide libraries were synthesized via oxidative cyclization of hydrazono-1,6-dihydropyrimidine-5-carboxamide intermediates by the application of Iodobenzenediacetate as a sole cyclizating agent. Here, we report one pot sequential strategy to generate corresponding triazolopyrimidines by condensation of preprepared -acylketene dithioacetals and arylamidines. Moreover, this process describes the application of presynthesized arylamidines which omits the transition metal catalyzed Suzuki-Miyaura cross coupling reaction hence signify the atom- and step-economic methodology.