Thiophene and its derivatives recently attracted researchers in exploring their potential as antioxidant agents (Madhavi et al., 2017). The main purpose of antioxidant is to neutralizes free radicals, which scavenge reactive oxygen species, may be high potent value in preventing the onset and propagation of oxidative diseases like neurovascular, autoimmune and cardiovascular diseases (kotaiah et al., 2012). The problem of drug resistance and generation of free radicals has promoted the researchers to study and explore for new compounds to combat the problems of infection and the associated risks from generation of free radicals
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