Synthesis of 1,3,4-Oxadiazoles and Their Medicinal Application - Patel, Haresh B.; Patel, Manish P.
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In present study, new series of 1,3,4-oxadiazole derivatives bearing benzothiazole motif have been synthesized via one-pot reaction in presence of ceric ammonium nitrate (CAN) catalyst. Despite the immense pharmacological effects of oxadiazole and benzothiazole, a modification on the oxadiazole nucleus may bring significant changes in pharmacological activities, and may provide new classes of therapeutically active compounds. The constitution of all the products was characterized using various spectroscopic techniques and subjected to in vitro antimicrobial, activity.

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Produktbeschreibung
In present study, new series of 1,3,4-oxadiazole derivatives bearing benzothiazole motif have been synthesized via one-pot reaction in presence of ceric ammonium nitrate (CAN) catalyst. Despite the immense pharmacological effects of oxadiazole and benzothiazole, a modification on the oxadiazole nucleus may bring significant changes in pharmacological activities, and may provide new classes of therapeutically active compounds. The constitution of all the products was characterized using various spectroscopic techniques and subjected to in vitro antimicrobial, activity.
Autorenporträt
Haresh a fait son M.Sc. avec une spécialisation en chimie analytique et son étude doctorale sous la direction du Dr. M. P. Patel Sir de l'Université S. P., V. V. Nagar. Il a une bonne maîtrise de la synthèse des intermédiaires de médicaments. Il travaille actuellement comme conférencier au L. J. Institute of Applied Science College, Ahmedabad.