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In this present work, different benzimidazole derivatives were synthesised by conventional method and it was optimised by distinct melting point, infra-red spectroscopy and UV absorbance. All the synthesised compounds showed good antimicrobial activity and further it was scrutinized for anti-tubercular activity where the compounds 2 and 3 showed good activity against H37Rv strain whereas compound 1 showed moderate activity. So these compounds can be further subjected to drug designing and evaluated by computational studies to yield excellent activity.

Produktbeschreibung
In this present work, different benzimidazole derivatives were synthesised by conventional method and it was optimised by distinct melting point, infra-red spectroscopy and UV absorbance. All the synthesised compounds showed good antimicrobial activity and further it was scrutinized for anti-tubercular activity where the compounds 2 and 3 showed good activity against H37Rv strain whereas compound 1 showed moderate activity. So these compounds can be further subjected to drug designing and evaluated by computational studies to yield excellent activity.
Autorenporträt
O Sr. Ahamed Mueen Mubeen completou a sua Licenciatura UG (B.Pharm) na Universidade SRM e a Licenciatura PG ( M.Pharm) na Faculdade de Medicina de Madurai. Actualmente está a fazer o seu trabalho como Professor Assistente no Swamy Vivekanandha College of Pharmacy, Elayampalayam Tiruchengode, Tamilnadu-637205, Índia.