Synthesis of Pyran Derivatives and Their Biological Activity - Patel, Dhaval B.
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In this book, we have discussed and to per best of our knowledge, we are the foremost in reporting water and ethanol as a solvent in the synthesis of ethyl 6-amino-5-cyano-2-methyl-4H-pyran-3-carboxylate derivative using Urea as a novel catalyst under the short period of time. This clearly shows that all substrates react smoothly under optimal conditions to give direct products with high yields. Subsequently, we demonstrated that benzaldehyde and the aromatic aldehydes bearing electron-withdrawing groups (such as nitro or halogens) require a shorter reaction time and give better yields than those bearing electron-donating groups.…mehr

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Produktbeschreibung
In this book, we have discussed and to per best of our knowledge, we are the foremost in reporting water and ethanol as a solvent in the synthesis of ethyl 6-amino-5-cyano-2-methyl-4H-pyran-3-carboxylate derivative using Urea as a novel catalyst under the short period of time. This clearly shows that all substrates react smoothly under optimal conditions to give direct products with high yields. Subsequently, we demonstrated that benzaldehyde and the aromatic aldehydes bearing electron-withdrawing groups (such as nitro or halogens) require a shorter reaction time and give better yields than those bearing electron-donating groups.
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Autorenporträt
Dhaval B. Patel é um investigador no domínio da química, com especialização em síntese orgânica.