Pyrrole is an essential building block in organic synthesis. Many aromatic compounds consist of the Pyrrole moiety have stimulating applications in the field of drug discovery, industry and in biology. A number of methods have been reported for the synthesis of pyrrole derivatives from starting material such as - and beta-dicarbonyl compounds, isonitriles. nitroalkanes and nitroalkenes, nitroolefins etc.. The use of multicomponent approaches to its preparation will continue to be an imperative effort in the future.
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