Nowadays nanotechnology is an enabling technology, developing incessantly in a vast manner procuring an exalting position in current rising research field in modern materials science. Prodigious interest on metal nanoparticles is expeditiously increasing in various fields. In particular, silver nanoparticles (AgNPs) are gaining predominant interest in present tremendous research due to their exquisite fascinating spectrum of physical and chemical properties such as structural, optical, electrical and antimicrobial along with their significant potential activity in a very wide range of applications. The present book emphasizes the feasibility of AgNPs synthesis through both chemical and green routes. This book is mainly focused on the optimization of physical and chemical properties of AgNPs and exploring their antimicrobial properties for usage in futuristic biological applications in medical field.