Synthesis of Sulfonamide by Metal Catalyzed Sulfonamidation - Abdelazeem, Nagwa
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A sulfonamide is the basis of several sulfa drugs. So a lot of work has gone into creating new sulfonamides using metal-free synthesis, which either uses sulfinate salts as intermediates or reacts amino compounds with sulfonyl chlorides. Unfortunately, the processes used to synthesize sulfonyl chlorides-such as oxidative chlorination of organ sulfur and electrophilic aromatic substitution with chlorosulfonic acid-often suffer from severe reaction conditions, a narrow range of applicability. So this book discusses numerous effective techniques such as transition-metals-catalyzed synthesis developed for the synthesis of sulfonamide.…mehr

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Produktbeschreibung
A sulfonamide is the basis of several sulfa drugs. So a lot of work has gone into creating new sulfonamides using metal-free synthesis, which either uses sulfinate salts as intermediates or reacts amino compounds with sulfonyl chlorides. Unfortunately, the processes used to synthesize sulfonyl chlorides-such as oxidative chlorination of organ sulfur and electrophilic aromatic substitution with chlorosulfonic acid-often suffer from severe reaction conditions, a narrow range of applicability. So this book discusses numerous effective techniques such as transition-metals-catalyzed synthesis developed for the synthesis of sulfonamide.
Autorenporträt
Dr. Nagwa Mourad Abdelazeem is a researcher at the National Research Centre, Egypt. She received Ph.D. of chemistry from Ain shams University, 2019. Her work is focusing on synthetic Heterocyclic and organometallic chemistry.