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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In autoimmune diseases the immune system attacks many different organs, tissues, and cells of the body. Examples include: systemic lupus erythematosis, rheumatoid arthritis, systemic sclerosis, and dermatomyositis. In contrast to systemic autoimmune diseases, organ-specific or tissue-specific autoimmune diseases such as diabetes mellitus type 1, Hashimoto''s thyroiditis, multiple sclerosis and myasthenia gravis affect only one organ or tissue type. For example, diabetes mellitus affects the islet cells in the pancreas, Hashimoto''s thyroiditis affects the thyroid gland, multiple sclerosis affects the brain, and myasthemia gravis affects the muscles.