The first book to comprehensively cover the field of systems genetics, gathering contributions from leading scientists.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
List of contributors; 1. An introduction to systems genetics Florian Markowetz and Michael Boutros; 2. Computational paradigms for analyzing genetic interaction networks Carles Pons, Michael Costanzo, Charles Boone and Chad L. Myers; 3. Mapping genetic interactions across many phenotypes in metazoan cells Christina Laufer, Maximilian Billmann and Michael Boutros; 4. Genetic interactions and network reliability Edgar Delgado-Eckert and Niko Beerenwinkel; 5. Synthetic lethality and chemoresistance in cancer Kimberly Maxfield and Angelique Whitehurst; 6. Joining the dots: network analysis of gene perturbation data Xin Wang, Ke Yuan and Florian Markowetz; 7. High content screening in infectious diseases: new drugs against bugs André P. Mäurer, Peter R. Braun, Kate Holden-Dye and Thomas F. Meyer; 8. Inferring genetic architecture from systems genetics studies Xiaoyun Sun, Stephanie Mohr, Arunachalam Vinayagam, Pengyu Hong and Norbert Perrimon; 9. Bayesian inference for model selection: an application to aberrant signalling pathways in chronic myeloid leukaemia Lisa E. M. Hopcroft, Ben Calderhead, Paolo Gallipoli, Tessa L. Holyoake and Mark A. Girolami; 10. Dynamic network models of protein complexes Yongjin Park and Joel S. Bader; 11. Phenotype state spaces and strategies for exploring them Andreas Hadjiprocopis and Rune Linding; 12. Automated behavioural fingerprinting of C. elegans mutants André E. X. Brown and William R. Schafer; Index.
List of contributors; 1. An introduction to systems genetics Florian Markowetz and Michael Boutros; 2. Computational paradigms for analyzing genetic interaction networks Carles Pons, Michael Costanzo, Charles Boone and Chad L. Myers; 3. Mapping genetic interactions across many phenotypes in metazoan cells Christina Laufer, Maximilian Billmann and Michael Boutros; 4. Genetic interactions and network reliability Edgar Delgado-Eckert and Niko Beerenwinkel; 5. Synthetic lethality and chemoresistance in cancer Kimberly Maxfield and Angelique Whitehurst; 6. Joining the dots: network analysis of gene perturbation data Xin Wang, Ke Yuan and Florian Markowetz; 7. High content screening in infectious diseases: new drugs against bugs André P. Mäurer, Peter R. Braun, Kate Holden-Dye and Thomas F. Meyer; 8. Inferring genetic architecture from systems genetics studies Xiaoyun Sun, Stephanie Mohr, Arunachalam Vinayagam, Pengyu Hong and Norbert Perrimon; 9. Bayesian inference for model selection: an application to aberrant signalling pathways in chronic myeloid leukaemia Lisa E. M. Hopcroft, Ben Calderhead, Paolo Gallipoli, Tessa L. Holyoake and Mark A. Girolami; 10. Dynamic network models of protein complexes Yongjin Park and Joel S. Bader; 11. Phenotype state spaces and strategies for exploring them Andreas Hadjiprocopis and Rune Linding; 12. Automated behavioural fingerprinting of C. elegans mutants André E. X. Brown and William R. Schafer; Index.
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