Rajib Deb, . P.P.Goswami, Vijay Kumar Saxena

Taking a prophylactic guard against Paratuberculosis

An attempt to use a novel gene as a vaccine candidate

• Broschiertes Buch

Produktbeschreibung

Paratuberculosis (Johne's disease) is a chronic infectious, granulomatous enteric disease of domestic and wild ruminants caused by Mycobacterium avium subsp. paratuberculosis (Map). To date, no effective prophylactic candidates are available for early protection against the paratuberculosis infection in animals. Numerous secretory proteins Map have shown to be potent immunogens and can be used as subunit vaccines/DNA vaccine and also can be used as a specific detection .This book, therefore provides a novel antigen family protein of Map, PPE (proline-proline-glutamic acid rich) an unique antigen, which has been characterized, expressed in prokaryotic as well as eukaryotic system to preliminary study it's existence and further immunoreactivity was studied alone as well as with an adjuvant model gamma interferon in murine model to elucidate its importance to develop DNA vasccine against paratuberculosis infection in animals.

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Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 92
• Erscheinungstermin: 2. Juli 2013
• Englisch
• Abmessung: 220mm x 150mm x 7mm
• Gewicht: 155g
• ISBN-13: 9783844323511
• ISBN-10: 3844323511
• Artikelnr.: 33238230

Autorenporträt

Graduated in Veterinary sciences and Post graduated in Animal Biotechnology from I.V.R.I.,India through ICAR JRF Examination. He has worked as a Senior Research Fellow under NAIP Project for six months. Presently he is pursuing PhD from I.V.R.I., India in Animal Biotechnology with the recipient of ICAR SRF grant.