High Quality Content by WIKIPEDIA articles! Tarpon Springs is a city in Pinellas County, Florida, United States. The population was 21,003 at the 2000 census. According to the U.S. Census Bureau's 2004 estimates, the city had a population of 22,554. Tarpon Springs is notable for having the highest percentage of Greek-Americans of any city in the U.S. According to the United States Census Bureau, the city of Tarpon Springs has a total area of 43.7 km² (16.9 mi²). 23.7 km² (9.1 mi²) of it is land and 20.0 km² (7.7 mi²) of it (45.83%) is water.