Technetium-99m Pharmaceuticals
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Radioactive drug development is a multi-disciplinary task, therefore, in a concerted effort, dedicated scientists and experts from different fields of specialisation have contributed to this book. It is presented in two sections. Section 1 contains basic principles and methods used for analysis, information on the chemistry of technetium and on radiopharmaceuticals labelled with technetium-99m, the characteristics of the 99 Mo/99mTc-generator, of 'kits' and formulations for in-vitro labelling, and special safety aspects for in-vivo labelling of blood cells. Section 2 contains monographs of…mehr

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Produktbeschreibung
Radioactive drug development is a multi-disciplinary task, therefore, in a concerted effort, dedicated scientists and experts from different fields of specialisation have contributed to this book. It is presented in two sections. Section 1 contains basic principles and methods used for analysis, information on the chemistry of technetium and on radiopharmaceuticals labelled with technetium-99m, the characteristics of the 99 Mo/99mTc-generator, of 'kits' and formulations for in-vitro labelling, and special safety aspects for in-vivo labelling of blood cells. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affecting in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients.
Autorenporträt
Radioactive drug development is a multi-disciplinary task, therefore, in a concerted effort, dedicated scientists and experts from different fields of specialization have contributed to this book. It is presented in two sections. Section 1 contains basic principles and methods used for analysis, information on the chemistry of technetium and on radiopharmaceuticals labeled with technetium-99m, the characteristics of the 99 Mo/99mTc-generator, of 'kits' and formulations for in-vitro labeling, and special safety aspects for in-vivo labeling of blood cells. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affection in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients.
Rezensionen
From the reviews:

"This nicely organized and clearly illustrated book provides an up-to-date resource for radiopharmacists and nuclear medicine physicians who compound and prescribe 99mTc-labeled radiopharmaceuticals. Radiochemists and those concerned with regulatory affairs also will be interested, and the book could be used as a primary text in nuclear medicine training programs. This outstanding book fills a void and is the first compilation of its kind in many years. We recommend it with the highest enthusiasm." (Susan Z. Lever and John R. Lever, Journal of Nuclear Medicine, May, 2009)
Aus den Rezensionen: "... Die Abschnitte sind überaus sorgfältig und übersichtlich gestaltet und stecken auch voller praktischer Tipps. Das Buch trägt umfassend bei zum Verständnis der Technetiumchemie und -pharmazie und somit zur Sicherung der Sachkunde im Umgang mit radioaktiven Arzneimitteln. Der Brückenschlag zur täglichen klinischen Nutzung ist sehr gut gelungen. Das Buch sollte überall dort zur Verfügung stehen, wo technetiummarkierte radioaktive Arzneimittel hergestellt und/oder verwendet werden ..." (U. Büll, in: Nuklearmedizin, 2008, Vol. 47, Issue 1, S. N10)